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"Pancreas"

Original Article

[English]
Surgical Treatment of Pancreatic Trauma in Children
Jae-Hyung Cho, Hyun-Young Kim, Sung-Eun Jung, Kwi-Won Park
J Korean Assoc Pediatr Surg 2013;19(2):98-107.   Published online December 24, 2013
DOI: https://doi.org/10.13029/jkaps.2013.19.2.98

Debates exist about the appropriate treatment for pancreatic trauma in children. We intended to examine the safety of the operation of pancreatic trauma in children. This is a retrospective study of 13 patients, younger than 15, who underwent surgery for pancreatic trauma, between 1993 and 2011 in Seoul National University Children's Hospital. Medical records were reviewed for mechanism of trauma, clinical characteristics, radiological findings, operation and outcomes. Organ injury scaling from the AAST (American Association for Surgery of Trauma) was used. All injuries were caused by blunt trauma. Patients with grade III, IV, and those who were difficult to distinguish grade II from IV, underwent surgery due to severe peritonitis. Three patients with grade II were operated for reasons of mesenteric bleeding, tumor rupture of the pancreas, and progression of peritonitis. Distal pancreatectomy was performed in 10 patients and subtotal pancreatectomy and pylorus preserving pancreaticoduodenectomy in 1 patient each. The remaining one underwent surgical debridement because of severe adhesions. The location of injury, before and after operation, coincided in 83.3%. The degree of injury, before and after the operation, was identical in all the patients except for those who were difficult to tell apart grade II from grade IV, and those cannot be graded due to severe adhesion. Postoperative complications occurred in 23.1%, which improved with conservative treatment. Patients were discharged at mean postoperative 12(range 8~42) days. Even though patients with complications took longer in time from diagnosis to operation, time of trauma to operation and hospital stay, this difference was not significant. In conclusion, When pancreatic duct injury is present, or patient shows deterioration of clinical manifestation without evidence of definite duct injury, or trauma is accompanied by other organ injury or tumor rupture, operative management is advisable, and we believe it is a safe and feasible method of treatment.

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Case Reports

[English]
Nonfunctioning Neuroendocrine Tumor of the Pancreas in a 15-year-old Girl: a Case Report
Kyungkeun Lee, Jinyoung Park
J Korean Assoc Pediatr Surg 2009;15(2):180-185.   Published online December 31, 2009
DOI: https://doi.org/10.13029/jkaps.2009.15.2.180

We report a case of nonfunctioning neuroendocrine tumor of the pancreas in a 15-year-old girl who presented with back pain. On physical examination, there was mild tenderness in the left upper quadrant of the abdomen. The patient had no pancreatic hormone-associated symptoms. An abdominal ultrasonography showed a well-demarcated hypervascular solid mass with calcification in the tail of the pancreas. An abdominal computed tomography scan showed a 6x5cm sized well-encapsulated enhancing solid mass with cystic component in the tail of the pancreas. Distal pancreatectomy was performed. Pathology revealed awell- differentiated nonfunctioning low grade malignant neuroendocrine tumor of the pancreas. The postoperative course was uneventful.

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[English]
Solid and Papillary Epithelial Neoplasm of the Pancreas in Children
Hyukjin Yoon, Jinyoung Park
J Korean Assoc Pediatr Surg 2006;12(1):32-40.   Published online June 30, 2006
DOI: https://doi.org/10.13029/jkaps.2006.12.1.32

Four children with solid and papillary epithelial neoplasm of the pancreas are reported. Three were girls. Mean age at operation was 12 years and 7 months (10-13 years). Clinical presentation included nausea, vomiting, and apalpable mass. One had hemoperitoneum due to tumor rupture. In two cases, tumors were in the body of the pancreas, and one the body and tail, and in one,the tail. Mean diameter of the tumors was 10.8 cm (8-15cm). Surgical procedures were distal pancreatectomy and splenectomy in 2 cases, distal pancreatectomy in one, and subtotal pancreatectomy and splenectomy in one. Mean follow-up period was 61 months (6-121 months). Three patients are still alive without any recurrence. However, in the one case of ruptured tumor, portal vein thrombosis and liver metastasis developed after subtotal pancreatectomy and splenectomy during the course of postoperative adjuvant chemotherapy.

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Original Articles

[English]
Solid and Papillary Epithelial Neoplasm of the Pancreas in a Child: A Case Report
Chang Won Jeon, Chang Seok Oh, Yun Soo Yang, Chang Rock Choi, Young Taek Lee, Jong Sool Ihm, Hyun I Son
J Korean Assoc Pediatr Surg 2005;11(1):46-52.   Published online June 30, 2005
DOI: https://doi.org/10.13029/jkaps.2005.11.1.46

Solid and papillary epithelial neoplasm (SPEN) of the pancreas is a rare tumor with low malignant potentiality that usually occurs in young females. Preoperative evaluation, especially radiologic tests, including ultrasonography and CT scan, is helpful in the diagnosis. These studies demonstrate a well-demarcated large mass with solid and cystic portions, frequently in the tail or body of the pancreas. Complete resection is usually curative, however local invasion and/or metastasis may occur. The authors report a case of a solid and papillary epithelial neoplasm of the pancreatic body in a 14-year old child at St. Benedict Hospital and review the literature.

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[English]
Solid and Papillary Cystic Neoplasm of Pancreas in Children
Sung Il Choi, Soo Myung Oh
J Korean Assoc Pediatr Surg 2000;6(2):134-138.   Published online December 31, 2000
DOI: https://doi.org/10.13029/jkaps.2000.6.2.134

Solid and papillary cystic neoplasm of pancreas is an uncommon low grade malignant tumor found predominantly in young female in their second or third decade of life, and amenable cure by surgical treatment. The authors report two cases of solid and papillary neoplasm of pancreas pathologically verified at Kyung Hee university hospital. The first case was 11-years old male patient and the other case was 12-years old male patient. Symptoms of two patients were abdominal discomfort, nausea and vomiting and abdominal pain in the female patient. CT finding of solid and papillary neoplasm of pancreas depict a well-demarcated mass with solid and cystic necrosis component. In female patient, large hematoma was shown. Gross findings of tumor revealed apparent encapsulation, cystic degeneration and hemorrhagic necrosis. Microscopically the tumors were characterized by distinctive solid and papillary patterns of cellular arrangement without local invasion. All patients were discharged and follow up without any problem.

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Case Report

[English]
A Case of Pseudocyst Originated from Ectopic Pancreas of Transverse Mesocolon Associated with Colonic Duplication
In Gyu Kim, Seok Joo Han, Kyung Mu Yang, Hogeun Kim, Myung Joon Kim, Jung Tak Oh, Eui Ho Hwang
J Korean Assoc Pediatr Surg 1998;4(1):79-84.   Published online June 30, 1998
DOI: https://doi.org/10.13029/jkaps.1998.4.1.79

We have treated a case of pseudocyst of transverse mesocolon in 3-year-old male child. Operative findings demonstrated that the pseudocyst originated in the transverse mesocolon, and was not connected to the pancreas. A colonic duplication was found incidentally near the pseudocyst. On microscopic examination, ectopic pancreatic tissue was noted in the transverse mesocolon. This pseudocyst was thought to have originated from the ectopic pancreas of the transverse mesocolon. This is the first reported case of pseudocyst originated from ectopic pancreas of the transverse mesocolon, combined with a colonic duplication. The pathogenesis is discussed.

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Original Article

[English]
Solid and Papillary Epithelial Neoplasm of the Pancreas in Children
Seok Ho Choi, Dae Yeon Kim, Kwi Won Park, Sung Eun Jung, Seong Cheol Lee, Woo Ki Kim, Ja Jun Jang
J Korean Assoc Pediatr Surg 1998;4(1):55-60.   Published online June 30, 1998
DOI: https://doi.org/10.13029/jkaps.1998.4.1.55

Six children with solid and papillary epithelial neoplasm of the pancreas were studied retrospectively. There were 2 boys and 4 girls. The mean age at operation was 11 years(range; 8-13years). Three patients had incidental abdominal mass, in two patients the mass was non-tender, in one patient the mass was tender. The minimum size of tumor was 6.5 × 6.0 cm and the maximum was 10.5 × 8.0 cm. Five tumors were located in the head of the pancreas, and the other one in the tail. Local invasion or metastasis was not noticed. Tumors were removed completely by performing the following operations: 3 pylorous preserving pancreaticoduodenectomy, 2 Whipple's operation and 1 distal pancreatectomy. There was no mortality. The histologic findings were characteristic. There were no recurrences during a follow-up of 0.5 to 12 years (mean; 5.0 years).

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Case Reports

[English]
A Case of Neonatal Sepsis after Operation of Annular Pancreas in Newborn
Chul Ho Lee, Wan Sup Kim, Eul Sam Chung
J Korean Assoc Pediatr Surg 1996;2(1):72-76.   Published online June 30, 1996
DOI: https://doi.org/10.13029/jkaps.1996.2.1.72

Annular pancreas is a rare congenital anomaly with the descending duodenum encircled by a ring of pancreatic tissue, which may cause partial or complete obstruction of the duodenum. In newborn, the symptoms can be those of duodenal stasis resulting from partial intestinal obstruction secondary to some degree of duodenal stenosis. A male newborn weighing 2.0 Kg was born by C-section delivery at 37 weeks' gestation to a 27-year-old mother who had a hydramnios. He was in relatively good condition at birth except regurgitation of saliva and intermittent apnea. A plain film of the abdomen showed the double-bubble of gas filled stomach and proximal duodenum, and upper gastrointestinal series showed a dilated proximal duodenum, with a complete obstruction of the descending duodenum. Intraoperative finding revealed encirclement of the duodenal second portion by pancreatic tissue. Duodenojejunostomy was performed. After the operation, he had developed two serious complications, neonatal septicemia by Enterobacter cloacae on postoperative day 12 and systemic candidiasis on postoperative day 19, and been managed with ventilatory support, antibiotics, and antifungal agents with recovery.

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[English]
Two Cases of Papillary Cystic Neoplasm of the Pancreas
Seung Hoon Choi, Eui Ho Hwang
J Korean Assoc Pediatr Surg 1995;1(1):79-84.   Published online June 30, 1995
DOI: https://doi.org/10.13029/jkaps.1995.1.1.79

Two cases with papillary cystic neoplasm of the pancreas are reviewed and discussed. Up to recently, the tumors have been misclassified as nonfunctioning islet cell tumor or carcinoma, acinar cell carcinoma, papillary cystadenocarcinoma, or pancreatoblastoma. It frequently has been managed with aggressive surgery such as pancreatoduodenectomy. The tumors are well encapsulated and the cut surfaces are characteristically solid and hemorrhagic. Ultrasonography and CT scan are the most useful tools for the diagnosis. The neoplasms usually behave like a very low grade malignancy, so complete removal is the treatment of choice for the tumor arising anywhere in the pancreas. We have a boy and a girl who have papillary cystic neoplasm. The boy was 12 years old and the girl was 14 years old. Both underwent distal panereatectomy and the progress were uneventfuL We have a boy and a girl who have papillary cystic neoplasm. The boy was 12 years old and the girl was 14 years old. Both underwent distal pancreatectomy and the progress were uneventful.

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Original Article

[English]
Comparison of Laparoscopic Versus Open Surgery for Solid Pseudopapillary Tumors in Children
Hwang, Honam , Youn, Joong Kee , Ko, Dayoung , Yang, Hee-Beom , Kim, Hyun-Young
Adv Pediatr Surg 2023;29(1):1-8.
DOI: https://doi.org/10.13029/aps.2023.29.1.1
Purpose
The aim of this study was to compare the clinical features and examine the safety and feasibility of laparoscopic surgery versus open surgery in children with solid pseudopapillary tumors (SPTs).
Methods
Patients under age 18 diagnosed with SPT who underwent surgery for the condition at our single institution from January 2005 to December 2019 were retrospectively analyzed. The demographics and postoperative outcomes in the two groups were compared according to the surgical method and tumor locations.
Results
The 25 patients consisted of 23 females and two males with a mean age at surgery of 13.2 years (range, 6 to 18 years). The lesions were located in the pancreatic head (n=7, 28.0%), and body or tail (n=18, 72.0%). Fifteen patients (60.0%) were treated with laparoscopic surgery. In all patients, there was no difference in intraoperative and postoperative outcomes between the two groups. When analyzed according to tumor location, complications including postoperative pancreatic fistula did not show significant differences with the surgical method in both the head group and body or tail group.
Conclusion
Compared to open surgery, the clinical outcomes and complication rate of the laparoscopic approach in pediatric SPT patients was not significantly different. Therefore, laparoscopic surgery for SPTs in pediatric patients may be a feasible option.
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Case Report

[English]
Situs inversus, polysplenia and annular pancreas are unusual anomalies individually, and are extremely rare in combination. A 3 years old boy presented with failure to thrive and symptoms of chronic upper gastrointestinal obstruction. After adequate radiological investigations, he was explored and managed with a duodeno-duodenostomy. and is doing well on a 1 year follow-up. The preoperative radiological assessment is of paramount importance, so as to avoid any intra-operative surprises.
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